New research identifies the brain chemicals and circuits involved in mental illnesses like schizophrenia, depression, and anxiety, giving potential new directions to their treatment. In addition, research with children shows that early-life depression and anxiety changes the structure of the developing brain.

Scientists are finding new tools to help understand neurodevelopmental disorders like autism and fragile X syndrome. Studies show in new detail how the brain's connections, chemicals, and genes interact to affect behavior.

The negative effects of depression in young people on the health of their hearts may be stronger than previously recognized. Depression or a history of suicide attempts in people younger than 40, especially young women, markedly increases their risk for dying from heart disease.

In a study conducted at 12 university-based research sites, there was wide variation in how best-estimate clinical diagnoses within the autism spectrum were assigned to individual children.

Impulsive individuals tend to display aggressive behavior and have challenges ranging from drug and alcohol abuse, to problem gambling and difficult relationships. They are less able to adapt to different social situations. Impulsivity is also a common feature of psychiatric disorders. New research shows that people may react this way, in part, because they have lower levels of GABA (gamma-aminobutyric acid), the most important inhibitory neurotransmitter, in a specific part of their brain involved in regulating self-control.